Advances in electrospinning techniques for synthesis of nanofibers loaded with herbal extracts and natural ingredients: A comprehensive review

Abstract

Electrospinning offers a versatile method for the synthesis of polymeric nanofibers integrated with natural compounds such as medicinal extracts, antibacterial agents, and antioxidants (e.g., Aloe vera, honey, curcumin). These composite fibers exhibit diverse potential applications spanning wound dressing, tissue engineering, drug delivery, and the food industry. Tailoring nanofiber morphologies and loading techniques enables modulation of release kinetics and controlled diffusion of extracts tailored to specific applications. Recent literature showcases an array of studies exploring the electrospinning of various polymers, including natural ingredients, for biomedical and industrial purposes. This article aims to compile and review methodologies for combining and encapsulating natural extracts within polymers via electrospinning synthesis method, alongside their applications. Our review presents a comprehensive analysis of electrospun nanofibers containing extracts and natural ingredients, encompassing their architectural diversity and factors influencing release kinetics. As more people become interested in natural materials, we expect to see a huge increase in research efforts in this field in the years to come.